Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.
Inhoudsopgave:
Foundations: Clinical rationale of IMRT.- The physical potential of IMRT.- Imaging the Lymph Nodes: CT, MRI, PET.- Morphology imaging.- IMRT plan optimization.- Practical IMRT planning.- IMRT Dose calculation.- IMRT delivery techniques.- Biological considerations of IMRT planning and delivery.- Image guided patient setup.- IMRT QA (European perspective).- IMRT QA (US perspective).- Advanced Image Guided and Biologically Driven Techniques: Functional and biological imaging (PET, SPECT, MRI-MRS).- Tumor imaging for dose painting.- Biological/functional-image guided optimization.- Biological optimization.- Image guided patient setup (and immobilization).- Adaptive IMRT (Linac).- Adaptive IMRT (Tomotherapy).- 4D CT.- 4D TP concepts.- Gating and tracking.- Clinical: Paranasal sinus.- Oropharynx.- Nasopharynx.- Larynx.- CNS, Skull Base and Paraspinal Tumors.- Chest.- Breast.- GI/Abdomen.- Prostate.- GYN.- Combination of IMRT with other modalities.- High precision.
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